Medical AIA five-domain score (0 to 10) for adults presenting to the emergency department with chest pain, estimating the 6-week risk of major adverse cardiac events (MACE: death, MI, or coronary revascularisation). Low scorers can often be discharged early; high scorers warrant an early invasive strategy.
| Band | Meaning |
|---|---|
| 0 to 3, low risk | Low short-term MACE risk (roughly 1.7% at 6 weeks). Early discharge is reasonable in many pathways, ideally with serial troponins per local protocol before disposition. |
| 4 to 6, moderate risk | Intermediate MACE risk (around 12 to 17%). Admit or observe with serial troponins and further non-invasive testing; do not discharge on the initial assessment alone. |
| 7 to 10, high risk | High MACE risk (around 50% or more in the derivation cohort). Treat as a likely acute coronary syndrome and pursue an early invasive strategy with cardiology involvement. |
Sum 0 to 2 points each for: History (suspicion), ECG, Age, Risk factors, and initial Troponin. Total 0 to 10. 0 to 3 low risk, 4 to 6 moderate, 7 to 10 high.The HEART score was described by Six, Backus, and Kelder (2008) and validated further by Backus, Mahler, and colleagues. This implementation is an educational tool and is not affiliated with the original authors or any guideline body.
A score of 0 to 3 carries a low 6-week MACE risk (around 1.7%) and supports early discharge in many pathways. Most accelerated protocols still require at least serial troponins, often with a high-sensitivity assay, before the patient goes home.
The original score uses the initial troponin. Real-world accelerated pathways such as the HEART Pathway add a repeat troponin (commonly at 3 hours, or a 0/1-hour high-sensitivity protocol) to improve safety before discharging low-risk patients.
TIMI and GRACE were derived in confirmed acute coronary syndrome to estimate prognosis. HEART was built specifically for undifferentiated emergency-department chest pain to triage who can be discharged early, and it performs well in that setting.
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